ASHWAGANDHA 700mg/ 60capsules

Ashwagandha extract 9% 700mg/ capsules, 60 capsules

Ashwagandha is best known for its anti-anxiety and stress-relieving effects. In addition, growing evidence supports the effectiveness of ashwagandha in improving total sleep time and sleep quality in people with and without insomnia, improves VO2max, and preliminary evidence suggests it also improves strength and recovery. Ashwagandha may also improve semen quality parameters in men with fertility problems.

Ashwagandha contains numerous bioactive compounds, namely alkaloids, flavonoids, glycosides, steroids and steroidal lactones. Steroid lactones include withanolides, which are believed to be responsible for most of the plant's benefits. Most of ashwagandha's benefits are at least partly due to its powerful antioxidant and anti-inflammatory properties. Ashwagandha may increase levels of antioxidant enzymes such as glutathione peroxidase and superoxide dismutase while inhibiting lipid peroxidation.

As part of its ability to reduce stress and anxiety, ashwagandha also appears to affect the hypothalamic-pituitary-adrenal axis - which plays a key role in the stress response — as evidenced by its ability to lower cortisol levels.

https://pubmed.ncbi.nlm.nih.gov/33650944

Furthermore, ashwagandha appears to alter the signaling of several neurotransmitters that are dysfunctional in anxiety disorders. Its ability to enhance GABA A receptor signaling is thought to underlie its sleep benefits.

Ashwagandha may improve endurance by increasing hemoglobin (a protein in red blood cells responsible for transporting oxygen to the rest of the body), but more research is needed to confirm this effect.

https://pubmed.ncbi.nlm.nih.gov/33670194

Ashwagandha's ability to improve reproductive health is attributed to its antioxidant effects coupled with its ability to increase testosterone levels. This effect is more noticeable in men with infertility and low testosterone levels, but preliminary evidence suggests that ashwagandha may also increase testosterone levels in healthy men.

https://pubmed.ncbi.nlm.nih.gov/29670898

In studies on ashwagandha, doses of 250-600 mg/day of the root extract were used. The most common dosing protocol is 600 mg/day divided into two doses, one taken in the morning with breakfast and the other in the evening. Evidence suggests that 600mg a day is superior to lower doses for improving sleep. Similarly, 600-1000 mg/day may be more beneficial than lower doses for those who train intensively. 

https://pubmed.ncbi.nlm.nih.gov/33670194

https://pubmed.ncbi.nlm.nih.gov/34559859