PE-22-28 10 mg

INFORMATION:

• The product (substance) is not a food or dietary supplement, and is not suitable for human consumption.
• Keep out of the reach of children.
• Keep the container tightly closed.
• Store in a dry, cool, shaded place; protect from moisture.
• Store only in original container.
• Avoid contact during pregnancy and lactation.
• Consult a physician if you feel unwell or have adverse reactions related to contact with the substance.

PE-22-28 is a peptide under investigation in the area of neuromodulation. Among other things, it is described in the experimental literature in the context of its effects on K2P-type potassium channels (TREK-1) - structures associated with the regulation of neuronal excitability and signaling in the central nervous system. For this reason, PE-22-28 appears in studies involving models related to mood, stress, neuronal plasticity and cognitive function.

In preclinical work, PE-22-28 is also sometimes analyzed in the context of models of nervous system damage and overload (e.g., ischemic or neurodegenerative models) - as a tool for assessing effects on selected cellular markers and pathways, including those related to repair processes and neuronal homeostasis.

In addition, PE-22-28 is described as a peptide with antimicrobial activity under laboratory conditions. In vitro studies analyze its interactions with microbial cell membranes, as well as its potential in models including bacteria and fungi, and selected markers of the inflammatory response. The evaluation of PE-22-28 on cell lines in the context of programmed cell death processes (in vitro studies) also appears in part of the publication.