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Obesity is a major public health problem. Experts around the world are conducting research to help understand the mechanisms of the disease, and thus improve therapeutic interventions. One aspect that researchers are looking into is the control of food intake. Gastrointestinal hormones are involved. Their function is to communicate the completion of food intake, which is why they are referred to as satiety signals. This group includes, among others, peptide (PYY), cholecystokinin and glucagon-like peptide-1. Ghrelin, which stimulates appetite, is distinguished by its opposite effect. Knowledge of gastrointestinal hormones is extremely valuable, so scientists are trying to identify compounds that would affect receptors linked to the centers responsible for regulating appetite. People who care about weight reduction can already reach for appetite suppressants.
How do appetite suppressants work?
One of the main causes of excessive eating is the disruption of mechanisms that are responsible for regulating appetite. If the satiety mechanism becomes impaired, we have a situation where the body does not send a signal to stop eating. Excitability of the hunger center can be caused by a variety of factors, including the action of the cerebral cortex and the paraventricular nucleus. In addition to hormones and neurotransmitters, the disorder can also be caused by taking certain medications, including barbiturates, clonidine and neuroleptics. If the brain does not receive a signal that the stomach is full, there is a risk of severe seizures, during which a person consumes huge amounts of food until his or her appetite is satisfied.
A product for reducing appetite can affect satiety mechanisms in different ways. Some products available to us reduce the secretion of gastric and intestinal juices, and further delay the process of gastric emptying of food. Such agents are referred to as intestinal brakes. Thus, their intake provides a short-term feeling of satiety, which is related to the delay of gastric motility. Other appetite suppressants speed up metabolism and suppress appetite.
Gastricity - how to reduce it? Suggestions from Biolab
One product worth paying special attention to is Tirzepatide, which contains GLP-1, the aforementioned glucagon-like peptide-1. This is a compound that is very much involved in regulating appetite. The described peptide stimulates insulin secretion, especially during the consumption of carbohydrate-rich foods. This helps to avoid peri-prandial increases in glycemia. Therefore, Tirzepatide is not only a means of reducing cravings, but also a preparation that can be extremely helpful for people struggling with type 2 diabetes. Active forms of GLP-1 are released from the intestine shortly after food consumption. It acts as an intestinal inhibitor and provides a feeling of satiety.
Tirzepatide is recommended for people struggling with obesity. In addition, other preparations for weight loss can be found at Biolab. It is worth mentioning that type 2 diabetes is very often accompanied by excessive body weight. Both overweight and obesity are associated with an increase in insulin resistance. GLP-1 peptide further improves lipid metabolism and ultimately reduces body weight. Its intake is also recommended for people with normal blood sugar levels, but who struggle with excessive cravings.
What appetite suppressants can you still find in our offer?
Another option for people who have problems with appetite suppression is Melanotan 2. It contains MT-2, a hormone analog that stimulates alpha-melanocytes. Its action involves binding to melanocortin receptors, specifically MC1, MC3, MC4 and MC5. As an appetite suppressant, it affects not only appetite, but also body weight and metabolism. It is related to MC3 and MC4 receptors, which are involved in controlling metabolic parameters and body weight. MC4 is mainly located in the brain and is very much involved in the control of appetite.
Melanotan 2 speeds up metabolism, and additionally contributes to the reduction of food intake. Appetite suppression is the initiating factor that allows you to lose pounds in the long term. The appetite suppressants we offer can also contribute to better functioning of other organs. Melanotan 2 enhances sexual desire, regardless of gender, and improves the quality of intercourse. We also recommend other preparations for libido available in our offer.
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