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The product is intended for research purposes
Brain functionStimulationVitalityNoopept (n-phenylacetyl-1-prolylglycine ethyl ester or GVS-111) is a nootropic ampakine similar in action to compounds from the racetam class, 1000 times stronger than piracetam, it was patented by the Russian pharmaceutical company JSC LEKKO Pharmaceuticals in 1996. Research shows that Noopept has similar effects but works differently than other nootropics in the racetam family. Noopept is not considered a true "racetam" because it lacks the 2-oxo-pyrrolidine core and is not detectable in blood or urine, but instead raises cycloprolylglycine (CPG) concentrations in the brain. Noopept is patented in both Russia and the USA. It is sold as a prescription drug in Russia and other countries that were part of the Soviet Union. And as a supplement in the United States.
Noopept also has an additional selective anxiolytic effect. Researchers believe this is partly due to Noopept's antioxidant effects, anti-inflammatory effects, and ability to prevent the neurotoxic effects of too much calcium and glutamate.
Noopept improves brain health and function in several ways. But two stand out in particular.
1. Noopept modulates AMPA and NMDA receptors and acetylcholine (ACh) transmission. Noopept increases cycloprolylglycine (CPG) levels in the brain. CPG is a dipeptide composed of proline and glycine that acts as a modulator of acetylcholine transmission and the AMPA and NMDA receptors.
When brain cells are deprived of oxygen, glutamate, which is the main excitatory neurotransmitter in the brain, does not work efficiently with neuroreceptors. The result can be a toxic buildup of glutamate in brain cells. Causing neuronal damage and eventually neuronal death. Noopept modulates neuroreceptor function, keeping glutamate transmission at a normal level. Protecting neurons and other brain cells from glutamate damage. Noopept has also been shown to modulate acetylcholine flow in the brain. Restoring the harmony of glutamate and acetylcholine functions not only protects the brain from damage. It can improve cognition, memory, learning, memorization, mood, and relieve anxiety.
2. Noopept increases Nerve Growth Factor (NGF), Brain-derived Neurotrophic Factor (BDNF) and mRNA. NGF and BDNF are directly related to neuroplasticity. This ability to repair and even grow new brain cells could have profound implications. Especially for people with neurodegenerative brain damage, such as Parkinson's or Alzheimer's disease. And even affecting the long-term reinforcement needed to develop long-term memory.
mRNA affects gene expression and intracellular communication in brain cells. This constant brain signaling and gene expression in brain cells is required for proper cognitive function. One study conducted in Moscow showed long-term use of NGF, BDNF and mRNA boosted with Noopept. The animals in this study showed no signs of tolerance. And long-term use of Noopept even intensified the neurotrophic effect. https://pubmed.ncbi.nlm.nih.gov/19240853/
noopept benefits include:
1. Increases Acetylcholine Signaling.
2. Increases the expression of BDNF and NGF protein receptors.
3. Protects the brain from glutamate toxicity.
4. Increases inhibitory neurotransmission.
5. Increases the content of dopamine in the brain
6. Improves cognitive functions
7. Better focus and concentration
8. Removes brain fog
9. Helpful with anxiety and depression
10. Helps with stress reduction
11. Improves memory and memorization (faster assimilation of knowledge)
12. may be useful in neurodegenerative diseases (Alzheimer, Parkinson)
Works well with other nootropic agents, oral dosage 10-30mg, sublingual/intranasal dosage 5-10mg.
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