DIOSMIN 500mg

DIOSMIN 500mg

Citrus fruits are a rich source of flavonoids, a class of polyphenolic secondary plant metabolites that play an important role in many biological processes. Diosmin is a flavonoid glycoside, often referred to as phlebotonic, used in the treatment of chronic venous insufficiency and hemorrhoids.  

Benefits

• Protective effect on the venous vessels 
• Increases vascular elasticity, improves blood return from lower limbs
• Reduces venous pressure
• Helps maintain proper blood circulation, reduces stasis 
• Reduces the feeling of heavy legs
• Helpful in the fight against cramps or swelling 
• Useful in the fight against varicose veins and haemorrhoids

Diosmin is a disaccharide derivative that consists of a diosmethine substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 through a glycosidic bond. It can be used as an antioxidant and anti-inflammatory agent. It is a glycosylflavone, rutinoside, disaccharide derivative, monomethoxyflavone and dihydroxyflavanone. It is derived from diosmetin.

https://www.drugs.com/npp/diosmin.html

Diosmin has antioxidant and anti-inflammatory properties and is used in the treatment of various diseases. It has been widely used since 1969 as a phlebotonic and vasoprotective agent for chronic venous insufficiency (CVI) and hemorrhoidal disease. 

1. With its antioxidant properties, Diosmin helps fight free radicals, preventing and reducing oxidative stress.

2. Reduces feelings of pain, swelling and tightness in the legs associated with chronic venous disease, while helping to increase vein tone and elasticity. 

3. May also provide relief for those suffering from secondary restless legs syndrome (RLS) caused by CVI. 

4. Diosmin has been indicated to improve glucose metabolism in diabetic disorders, while providing answers for those struggling with neurological problems such as Alzheimer's disease. 

5. It may also contribute to the treatment of melanoma and colon cancer, lymphedema and chromosomal damage associated with radiation therapy, and women's health problems related to the reproductive system.

6. Diosmin has been used to improve postoperative cardiac function in adults undergoing coronary artery bypass graft (CABG) surgery, as well as for pelvic congestion and varicose veins in men.

https://pubchem.ncbi.nlm.nih.gov/compound/Diosmin#section=Protein-Binding